基本介绍

博士,助理教授,硕导

 

专业方向

1. 食品营养学与功能食品

2. 食品风味化学与分子生物学

 

人才项目

百人计划    

 

教育经历    

2013.07-2017.12,新加坡国立大学,化学系,食品科学与技术,博士

2008.09-2012.06,华中农业大学,食品科技学院,食品科学,学士

 

工作经历

2024.04至今,中山大学,农业与生物技术学院,助理教授

2020.12-2024.03,中山大学,农学院 助理教授

2020.05-2020.10,慕尼黑工业大学,莱布尼兹食品系统生物学研究所,博士后

2018.12-2020.04,慕尼黑工业大学,食品化学与分子感官实验室,博士后

2018.06-2018.11,万科企业股份有限公司,项目科学家

2017.10-2018.06,新加坡国立大学公共卫生学院,科研助理/博士后

 

科研成果    

发表论文:(#共同一作,*通讯作者)

1. Cai, X., Lin, Z., Liu, L., Yan, W., Wang, Z., Zhang, Y., Chen, X. and Liang, D., 2025. Rethinking the Cucurbitane-Type Triterpenoid Profile of Bitter Gourd (Momordica charantia L): The Chemical Transformation of Momordicine I in Solution. Journal of Agricultural and Food Chemistry(IF 5.7,一区Top)

2. Cai, X., Li, H., Liao, M., Zheng, Q., Chen, H., Zhang, Y., Chen, X. and Liang, D., 2025. Discovery of major bitter-tasting compounds from bitter gourd (fruit of Momordica charantia L.) by application of the sensomics approach. Food Bioscience, p.106107. (IF 4.8,一区)

3. Cai, X., Lin, Z., Zheng, Q., Liao, M., Li, H., Feng, H., ... & Liang, D. (2024). Major Bitter-Tasting Compounds from the Dichloromethane Fraction of Bitter Gourd (Fruit of Momordica charantia L.) Extract and Their Precursors. Journal of Agricultural and Food Chemistry72, 40, 22237–22249 (IF 5.7,一区Top)

4. Liang, D., Dirndorfer, S., Somoza, V., Krautwurst, D., Lang, R., & Hofmann, T. (2022). Metabolites of Key Flavor Compound 2, 3, 5-Trimethylpyrazine in Human Urine. Journal of Agricultural and Food Chemistry, 70(48), 15134-15142. (IF 5.7,一区Top)

5. Zhang, Y., Yang, X., Tang, H., Liang, D., Wu, J., & Huang, D. (2019). Pyrenediones as Versatile Photocatalysts for Oxygenation Reactions with in situ Generation of Hydrogen Peroxide under Visible Light. Green Chemistry. (IF 9.43,一区)

6. Lin, Y., Yang, X., Lu, Y., Liang, D., & Huang, D. (2019). Isothiocyanates as H2S donors triggered by cysteine: Reaction mechanism and structure and activity relationship. Organic Letters, 21(15), 5977-5980. (IF 6.55, 一区)

7. Li, Z., Lee, H. W., Liang, X., Liang, D., Wang, Q., Huang, D., Ong, C. N.* Profiling of Phenolic Compounds and Antioxidant Activity of 12 Cruciferous Vegetables. Molecules 2018, 23(5), 1139. (IF 3.27, 三区)

8. Sun, M., Krishnakumar, S., Zhang, Y., Liang, D., Yang, X., Wong, M. W., Wang, S., Huang, D.* Singlet oxygen probes made simple: Anthracenylmethyl substituted fluorophores as reaction-based probes for detection and imaging of cellular 1O2. Sensors and Actuators B: Chemical 2018 271, 346-352.  (IF 6.39, 一区)

9. Liang, D., Zhang, Y., Wu, Z., Chen, Y. J., Yang, X., Sun, M., Ni, R., Bian, J., Huang, D.* A near infrared singlet oxygen probe and its applications in in vivo imaging and measurement of singlet oxygen quenching activity of flavonoids. Sensors and Actuators B: Chemical 2018, 266, 645-654.  (IF 6.39, 一区)

10. Zhang, Y., Yao, W., Liang, D., Sun, M., Wang, S., Huang, D.* Selective detection and quantification of tryptophan and cysteine with pyrenedione as a turn-on fluorescent probe. Sensors and Actuators B: Chemical 2018, 259, 768-774. (IF 6.39, 一区)

11. Yao, W., Sun, M., Zhang, Y., Yang, H., Liang, D., Wu, H., Ni, R., Wong, M. W., Huang, D.* Photo-induced C–H bond activation of N, N′-dialkylethylenediamine upon aza-Michael addition to 1, 8-pyrenedione: facile synthesis of fluorescent pyrene derivatives. Organic Chemistry Frontiers 2018, 5(10), (IF 4.85, 二区)

12. Liang, D., Bian, J., Deng, L.-W., Huang, D.* Cyclic polysulphide 1, 2, 4-trithiolane from stinky bean (Parkia speciosa seeds) is a slow releasing hydrogen sulphide (H2S) donor. Journal of Functional Foods 201735, 197-204. (IF 3.7, 一区)

13. Lehnhardt, F. #Liang, D. #, Chen, Q., Tocmo, R., Rychlik, M., & Huang, D.* Effects of S-allyl glutathione disulphide and vinyl-dithiin isomers from garlic on the chronological lifespan of Saccharomyces cerevisiae. Journal of Functional Foods 2017, 37, 650-657. (IF 3.7, 一区)

14. Yan, X., Wu, H., Wu, Z., Hua, F., Liang, D., Sun, H., Yang, Y., Huang, D., Bian, J.-S.* The new synthetic H2S-releasing SDSS protects MC3T3-E1 osteoblasts against H2O2-induced apoptosis by suppressing oxidative stress, inhibiting MAPKs, and activating the PI3K/Akt pathway. Frontiers in Pharmacology 2017, 8. (IF 4.4,二区)

15. Tocmo, R., Wu, Y., Liang, D., Fogliano, V., Huang, D.* Boiling enriches the linear polysulfides and the hydrogen sulfide-releasing activity of garlic. Food Chemistry 2017, 221, 1867-1873. (IF 6.3,一区)

16. Tocmo, R., Lai, A. N., Wu, Y., Liang, D., Fogliano, V., Huang, D.* Organosulphide profile and hydrogen sulphide-releasing activity of garlic fermented by Lactobacillus plantarum. Journal of Functional Foods 2017, 30, 254-259. (IF 3.7, 一区)

17. Tocmo, R., Liang, D., Wang, C., Poh, J., Huang, D.* Organosulfide profile and hydrogen sulfide-releasing capacity of stinky bean (Parkia speciosa) oil: Effects of pH and extraction methods. Food Chemistry 2016, 190, 1123-1129. (IF 6.3,一区)

18. Liang, D., Wu, H., Wong, M. W., Huang, D.* Diallyl trisulfide is a fast H2S donor, but diallyl disulfide is a slow one: the reaction pathways and intermediates of glutathione with polysulfides. Organic Letters 201517, 4196-4199. (IF 6.55,一区)

19. Tocmo, R., Wang, C., Liang, D., Huang, D.* Organosulphide profile and hydrogen sulphide-releasing capacity of garlic (Allium sativum L.) scape oil: Effects of pH and cooking. Journal of Functional Foods 2015, 17, 410-421. (IF 3.7,一区)

20. Liang, D., Wang, C., Tocmo, R., Wu, H., Deng, L.-W., Huang, D.* Hydrogen sulphide (H2S) releasing capacity of essential oils isolated from organosulphur rich fruits and vegetables. Journal of Functional Foods 201514, 634-640. (IF 3.7,一区)

21. Feng, W., Teo, X.-Y., Novera, W., Ramanujulu, P. M., Liang, D., Huang, D., Moore, P. K., Deng, L.-W.* Dymock, B. W., Discovery of new H2S releasing phosphordithioates and 2, 3-dihydro-2-phenyl-2-sulfanylenebenzo [d][1, 3, 2] oxazaphospholes with improved antiproliferative activity. Journal of Medicinal Chemistry 2015, 58, 6456-6480. (IF 5.66,一区)

22. Tocmo, R., Liang, D., Lin, Y., Huang, D.* Chemical and biochemical mechanisms underlying the cardioprotective roles of dietary organopolysulfides. Frontiers in Nutrition 2015, 2, 1.

23. Wu, H., Krishnakumar, S., Yu, J., Liang, D., Qi, H., Lee, Z. W., Deng, L. W., Huang, D.* Highly Selective and Sensitive Near‐Infrared‐Fluorescent Probes for the Detection of Cellular Hydrogen Sulfide and the Imaging of H2S in Mice. Chemistry–An Asian Journal 2014, 9, 3604-3611. (IF 4.38,二区)

24. Zhou, Q., Liang, D., Deng, A., Zhang, J.* Wu, C., Nie, Z., Wang, Y., Antitussive, expectorant and bronchodilating effects of ethanol extract of Sorghum bicolor (L.) Moench roots. Journal of Ethnopharmacology 2013, 149(1), 297-302. (IF 2.93,三区)

25. Liang, D.#, Zhou, Q.#, Zhang, J.* Gong, W., Xu, C., Li, B., Wang, Y., Li, J. A novel chenodeoxycholic acid-verticinone ester induces apoptosis and cell cycle arrest in HepG2 cells. Steroids 201277, 1381-1390. (IF 2.80, 三区)

26. Liang, D.#, Zhou, Q.#, Gong, W., Wang, Y., Nie, Z., He, H., Li, J., Wu, J., Wu, C., Zhang, J.* Studies on the antioxidant and hepatoprotective activities of polysaccharides from Talinum triangulareJournal of Ethnopharmacology 2011136, 316-321. (IF 3.014,三区)

 

科研项目:

1. 国家自然科学基金青年项目, 32302266, 苦瓜中的呈苦物质解析及受体识别机制, 2024/01-2026/12, 30万元, 主持。

2. 深圳市科创委基础研究专项(深圳市自然科学基金)面上项目,JCYJ20220530145450001,香菇中的天然硫化氢供体研究,2022/10–2025/10,30万元,主持。

3. 中山大学“百人计划”引进人才基本启动费,20万,2020.12-2022.12. 主持