基本介绍
夏忆寒
博士 副教授 硕导（植物保护/资源利用与植物保护）
专业方向
农业昆虫与害虫防治
研究方向：昆虫化学生态学，代谢工程与合成生物学。主攻方向一:基因编辑重构异源微生物及植物的代谢通路, 用于昆虫信息素的合成及释放, 从而通过绿色手段进行害虫综合治理。主攻方向二: 植物挥发物的释放机理及调控研究。主攻方向三: 昆虫性信息素合成机制研究。主攻方向四: 用合成生物学的方法对酵母进行基因改造, 用于生产具有害虫防控作用的抗菌肽。
课题组博士后招聘要求：1. 具有生物学、农学、生物信息学或基因组学等相关专业博士学位。2. 具有生物化学与分子生物学、化学生态学、代谢工程与合成生物学或生物信息学等领域专业背景；在本领域至少发表一篇专业期刊论文。3. 有较好的英文写作和阅读能力。4. 能够能独立设计并开展研究工作。应聘材料：（1）个人简历；（2）自荐信；（3）毕业论文或代表性成果；（4）应聘者认为其他必要的证明材料。应聘者请将上述应聘材料以PDF形式发送至xiayh23@mail.sysu.edu.cn。
人才项目
百人计划
教育经历
2015.11-2020.03，瑞典隆德大学（Lund University），生物学，博士，师从Christer Löfstedt院士
2012.09-2015.06，南京农业大学，农业昆虫与害虫防治，硕士
2008.09-2012.06，南京农业大学，生态学，学士
工作经历
2024.04至今，中山大学，农业与生物技术学院，副教授
2023.04-2024.03，中山大学，农学院，副教授
2022.04-2023.04，瑞典查尔姆斯大学（Chalmers University of Technology）, 生物与生物工程学院（Department of Biology and Biological Engineering）, 系统与合成生物学系（Systems and Synthetic Biology），Researcher，实验室带头人Jens Nielson院士
2020.04-2022.04，瑞典查尔姆斯大学（Chalmers University of Technology）, 生物与生物工程学院（Department of Biology and Biological Engineering）, 系统与合成生物学系（Systems and Synthetic Biology），博士后，实验室带头人Jens Nielson院士
科研成果
发表论文
1.Xia, Y. H., Ding, B. J., Dong, S. L., Wang, H. L., Hofvander, P., Löfstedt, C. (2022) Release of Moth Pheromone Compounds from Nicotiana benthamiana upon Transient Expression of Heterologous Biosynthetic Genes. BMC Biology 20, 80 (SCI 1 区 top) (5 年 IF 8.816)
2. Xia, Y. H., Wang, H. L., Ding, B. J., Svensson, G. P., Jarl-Sunesson, C., Cahoon, E. B., Hofvander, P., Löfstedt, C. (2021) Green Chemistry Production of Codlemone, The Sex Pheromone of the Codling Moth (Cydia pomonella), by Metabolic Engineering of the Oilseed Crop Camelina (Camelina sativa). Journal of Chemical Ecology 47, 950-967. http://doi.org/10.1007/s10886-021-01316-4 (特约专刊，作为重要贡献奉献于国际化学生态学杂志一期特刊:纪念 Prof. Dr. Dr. hc mult. Wittko Francke)
3. Ding, B. J.*#, Xia, Y. H.*#, Wang, H. L., Andersson F., Hedenström E., Gross J., Löfstedt, C. (2021) Biosynthesis of the Sex Pheromone Component (E,Z)-7,9-Dodecadienyl Acetate in the European Grapevine Moth, Lobesia botrana, Involving Δ11 Desaturation and an Elusive Δ7 Desaturase. Journal of Chemical Ecology 47, 248-264. https://doi.org/10.1007/s10886-021-01252-3 (*, 共同一作; #, 通讯作者)
4. Löfstedt, C. (导师), Xia, Y. H. (2021) Biological Production of Insect Pheromones in Cell and Plant Factories. In: 2nd Insect Pheromone Biochemistry and Molecular Biology. Eds. Gary Blomquist, Richard Vogt. Elsevier, Academic Press. pp 89-121. ISSN/eISSN: 0361-3682 / 1873-6289 (综述; 著作第三章)
5. Xia, Y. H. #, Ding, B. J., Wang, H. L., Jarl-Sunesson, C., Hofvander, P., Löfstedt, C. (2020) Production of Moth Sex Pheromone Precursors in Nicotiana spp. by Agrobacterium-mediated Stable Transformation. Journal of Pest Science 93, 1333-1346. (#, 通讯作者) (SCI 1 区 top) (5 年 IF 5.955)
6. Xia, Y. H. (2020) Plants as Factories for Insect Pheromone Production: Deciphering and Reconstructing Sex Pheromone Biosynthetic Pathways of Female Moths. Lunds Universitet, Media-Tryck. ISBN 978-91-7895-428-5
7. Xia, Y. H. #, Zhang, Y. N., Ding, B. J., Wang, H. L., Löfstedt, C. (2019) Multi-Functional Desaturases in Two Spodoptera Moths with Δ 11 and Δ 12 Desaturation Activities. Journal of Chemical Ecology 45, 378-387. (#, 通讯作者)
8. Xia, Y. H., Zhang, Y. N., Hou, X. Q., Li, F., Dong, S. L. (2015) Large Number of Putative Chemoreception and Pheromone Biosynthesis Genes Revealed by Analyzing Transcriptome from Ovipositor-pheromone Glands of Chilo suppressalis. Scientific Reports 5, 7888.
9. Zhang, Y. N., Xia, Y. H., Zhu, J. Y., Li, S. Y., Dong, S. L. (2014) Putative Pathway of Sex Pheromone Biosynthesis and Degradation by Expression Patterns of Genes Identified from Female Pheromone Gland and Adult Antenna of Sesamia inferens (Walker). Journal of Chemical Ecology 40, 439-451.
10. Zhang, Y. N., Jin, J. Y., Jin, R., Xia, Y. H., Zhou, J. J., Deng, J. Y., Dong, S. L. (2013) Differential Expression Patterns in Chemosensory and Non-chemosensory Tissues of Putative Chemosensory Genes Identified by Transcriptome Analysis of Insect Pest the Purple Stem Borer Sesamia inferens (Walker). PloS one 8, e69715.
国际专利
- Xia, Y. H., Löfstedt, C., Hofvander, P., Ding, B. J., Wang, H. L., Cahoon, E. B., Neto, A. M. (2023) Methods of Producing Insect Pheromones. PCT Application No.: PCT/US21/16974 Ref: ISCA-0381N, Pending
- Löfstedt, C., Hofvander, P., Ding, B. J., Xia, Y. H., Wang, H. L., Jarl-Sunesson C., Cahoon, E. B. Neto, A. M. (2021) METHODS OF PRODUCING INSECT PHEROMONES. US Patent App. 17/169,444
科研项目
瑞典创新机构 (Vinnova), 开发酿酒酵母作为新一代药物发现和生产平台(Develop baker´s yeast Saccharomyces cerevisiae as an advanced drug discovery and production platform), 2020–2023, 420万元, 进行中, 参与
欧盟地平线 2020 研究和创新计划 (European Union’s Horizon 2020 research and innovation programme), No. 760798, 发展新型高效昆虫信息素合成方法 (OLEFINE), 2018–2022, 700万元, 已结题, 参与
卡尔特里格科学研究基金会 (Carl Trygger Foundation for Scientific Research), No. CTS 14:307–CTS KF17:15, 利用细胞工厂生产昆虫信息素 (Biological factories as platforms for insect pheromone production), 2016–2020, 280万元, 已结题, 参与
隆德皇家生理学会 (Royal Physiographic Society in Lund), No. 2018–39871, 解析二化螟信息素合成路径及分子机制 (Functional characterization of putative pheromone biosynthetic genes in the rice stem border, Chilosuppressalis), 2018–2019, 已结题, 主持
Jörgen Lindström 的奖学金基金 (Jörgen Lindström’s Scholarship Fund), 利用植物工厂生产并释放昆虫信息素, 用于害虫综合治理 (Plants as factories for insect pheromone production and release), No. 2018–YHX, 2018–2019, 已结题, 主持
瑞典战略研究基金会 (Swedish Foundation for Strategic Research), No. RBP 14-0037, 未来油料作物的发展与应用 (Oil Crops for the Future), 2015–2019, 2100万元，参与
瑞典研究委员会 (Swedish Research Council (VR)), 蛾类昆虫信息素进化分析 (Evolution of pheromones in moths )， 2016–2019, 210万元, 已结题，参与
瑞典研究委员会 (Swedish Research Council (Formas) ), No. 2010-857–2015-1336, 信息素啤酒厂——可持续半合成生产昆虫信息素的酵母细胞工厂(The pheromone brewery - a yeast cell factory for sustainable semisynthetic production of insect pheromones), 2016–2018, 285万元, 已结题, 参与
瑞典研究与高等教育国际合作基金会 (Swedish Foundation for International Cooperation in Research and Higher Education), 鳞翅目昆虫的信息素进化分析 (Evolution of pheromones in Lepidoptera species), 2016–2017, 73万元, 参与
社会兼职
担任Frontiers in Bioengineering and Biotechnology客座编辑。
Genomics, PLOS Biology, Journal of Asia-Pacific Entomology, International Journal of Molecular Sciences, Frontiers in Physiology, PeerJ等期刊同行审稿人。
